Good Laboratory Practices (GLP) are a set of principles that ensure the reliability of the reports issued by a laboratory and are applied in studies related to the safe use of products for human health, plants, animal health and the environment. Laboratories recognized for adherence to the GLP principles have:
Increased reliability, traceability and consistency
Dissemination of information
Non-acceptance of errors
Laboratories recognized for adherence to GLP principles besides having several benefits from a structured quality system are still well regarded by regulatory agencies.
The Flux GLP system consists of six electronic data management forms conforming to GLP principles that are extended to several laboratories.
The forms that compose Flux GLP are:
Equipment: It allows to register detailed information of each equipment, besides providing management information on maintenance, cleaning, calibration and uses among others.
Teams and Responsibilities: It allows to register information about the team involved in the job. In addition to the personal data information such as academic training, curriculum, roles and responsibilities, skills and qualification among others, may also be recorded.
Standard Operating Procedures (SOP): It allows the management of SOPs, allowing the entry of new documents and their approval. Authorized persons can manage records and reviews of these documents, which are saved in an easy-to-view history.
Test and Reference Substances: It allows the management of test and reference substances. Records are maintained including substance characterization, date of receipt, storage and use among others.
Study Plan: It allows the storage of information that must be inserted before, during and after a study. Information about dates, sponsor, methods, experiment sites, results, changes (deviations and menus), and final evaluation among others, can be stored.
System Test: It allows the management of information about the system used for the tests, be it animal, plant or other cellular, subcellular, chemical or physical system or the combination of these, which are defined as object of study. Records of origin, conditions, and date of arrival at the laboratory are maintained among others.